Varsani Lab - the viral kind
We are a wild 'viral' molecular virology research group that works across ecosystems studying viral dynamics.


Our broader objectives are to
- Study viral dynamics in Ross Sea (Antarctica) ecosystem which is recognised as anthropogenically the least-altered marine system on the planet with no evidence indicating introduction or range expansion of any species thus far, despite its changing physical environment.
- Unravel the viral evolutionary dynamics as a consequence of climate change.
- Study viral ecological interaction networks within a microbiome to unravel the dynamics of pathogen emergence.
Arvind Varsani
I am a molecular virologist who works across ecosystems from plants to animals and from the tropics to the Antarctic. My research uses a combination of traditional virology, microscopy (including transmission electron microscopy), molecular and cellular biology techniques in conjunction with modern sequencing techniques, synthetic biology and bioinformatics to characterise viruses and understand their dynamics.
Arizona State University, Tempe, USA
6/2023 - current: Professor at the Biodesign Institute and School of Life Sciences
07/2016 - 6/2023: Associate Professor at the Biodesign Institute and School of Life Sciences
University of Canterbury, Christchurch, New Zealand
02/2009 - 07/2016: Senior lecturer / researcher in School of Biological Sciences
University of Cape Town, Cape Town, South Africa
07/2003 - 09/2008: Lecturer in the Structural Biology Research Unit
University of Cape Town, Cape Town, South Africa
1998 - 2003: PhD in Molecular and cell biology
Loughborough University, Loughborough, England
1993 - 1997: BSc, DIS in Medicinal and Pharmaceutical Chemistry


Publications
Identification and characterization of a polyomavirus in the thornback skate (Raja clavata)
Identification and characterization of a polyomavirus in the thornback skate (Raja clavata)Abrantes, J., Varsani, A., Pereira, P., Maia, C., Farias, I., Veríssimo, A. & Neves, F., Dec 2023, In: Virology Journal. 20, 1, 190.Research output: Contribution to journal › Article › peer-review
Author Correction: Guidelines for public database submission of uncultivated virus genome sequences for taxonomic classification (Nature Biotechnology, (2023), 41, 7, (898-902), 10.1038/s41587-023-01844-2)
Author Correction: Guidelines for public database submission of uncultivated virus genome sequences for taxonomic classification (Nature Biotechnology, (2023), 41, 7, (898-902), 10.1038/s41587-023-01844-2) Adriaenssens, E. M., Roux, S., Brister, J. R., Karsch-Mizrachi, I., Kuhn, J. H., Varsani, A., Yigang, T., Reyes, A., Lood, C., Lefkowitz, E. J., Sullivan, M. B., Edwards, R. A., Simmonds, P., Rubino, … Read more
Guidelines for public database submission of uncultivated virus genome sequences for taxonomic classification
Guidelines for public database submission of uncultivated virus genome sequences for taxonomic classification Adriaenssens, E. M., Roux, S., Brister, J. R., Karsch-Mizrachi, I., Kuhn, J. H., Varsani, A., Yigang, T., Reyes, A., Lood, C., Lefkowitz, E. J., Sullivan, M. B., Edwards, R. A., Simmonds, P., Rubino, L., Sabanadzovic, S., Krupovic, M. & Dutilh, B. E., … Read more
Genomes of Single-Stranded DNA Viruses in a Fecal Sample from South Polar Skua (Stercorarius maccormicki) on Ross Island, Antarctica
Genomes of Single-Stranded DNA Viruses in a Fecal Sample from South Polar Skua (Stercorarius maccormicki) on Ross Island, Antarctica Shick, S. R. A., Elrod, M. L., Schmidt, A., Kraberger, S., Ainley, D. G., Ballard, G. & Varsani, A., Jun 2023, In: Microbiology Resource Announcements. 12, 6 Research output: Contribution to journal › Article › peer-review
Evolution of anelloviruses from a circovirus-like ancestor through gradual augmentation of the jelly-roll capsid protein
Evolution of anelloviruses from a circovirus-like ancestor through gradual augmentation of the jelly-roll capsid protein Butkovic, A., Kraberger, S., Smeele, Z., Martin, D. P., Schmidlin, K., Fontenele, R. S., Shero, M. R., Beltran, R. S., Kirkham, A. L., Aleamotu’a, M., Burns, J. M., Koonin, E. V., Varsani, A. & Krupovic, M., 2023, In: Virus Evolution. … Read more
Metagenomics reveals the structure of Mastrevirus-host interaction network within an agro-ecosystem
Metagenomics reveals the structure of Mastrevirus-host interaction network within an agro-ecosystem Claverie, S., Hoareau, M., Chehida, S. B., Filloux, D., Varsani, A., Roumagnac, P., Martin, D. P., Lett, J. M. & Lefeuvre, P., 2023, In: Virus Evolution. 9, 2, vead043. Research output: Contribution to journal › Article › peer-review